Animal Models of Human Pathology 2016
نویسندگان
چکیده
1 Istituto per l’Endocrinologia e l’Oncologia Sperimentale (IEOS), CNR, 80131 Naples, Italy 2Santiago University Clinical Hospital, Instituto de Investigación Sanitaria de Santiago (IDIS), 15706 Santiago de Compostela, Spain 3Human Cancer Genetics Program/CCC, The Ohio State University, Columbus, OH 43210, USA 4Department of Clinical and Molecular Medicine, Sapienza University of Rome, 00100 Rome, Italy
منابع مشابه
Animal and cellular models of human disease.
In this eighteenth (2016) Annual Review Issue of The Journal of Pathology, we present a collection of 19 invited review articles that cover different aspects of cellular and animal models of disease. These include genetically-engineered models, chemically-induced models, naturally-occurring models, and combinations thereof, with the focus on recent methodological and conceptual developments acr...
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The recent development of gene editing tools and methodology for use in livestock enables the production of new animal disease models. These tools facilitate site-specific mutation of the genome, allowing animals carrying known human disease mutations to be produced. In this review, we describe the various gene editing tools and how they can be used for a range of large animal models of disease...
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Liver flukes-induced pathological changes in liver parenchyma and biliary passages are so severe that, in some cases, may cause total physiologic dysfunction. The human disease is endemic to some parts of the country, and there were two vast epidemics of the human fascioliasis in Gilan province, northern most part of the country. According to WHO reports , the human disease is prevalent in Gila...
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Background: The aim of this study was to evaluate and compare the hepatotoxicity as well as antioxidants activities of hydromethanolic extract of six common traditional species (Origanum vulgar, Pterocarya fraxinifolia, Ferula assafoetida, Artemisia dracunculus, Rosmarinus officinalis, and Valerian officinalis) in order to find a safe antioxidant source. Methods: This research project was perf...
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Sir, We applaud the recent Journal of Pathology Annual Review Issue on Models of Human Disease. This highlighted the need to identify robust and relevant models to address human disease, recognising their strengths and limitations [1], at the same time being cognisant of employing the principles of the 3Rs (Replacement, Reduction, and Refinement) [2] in research, and improving experimental repr...
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ورودعنوان ژورنال:
دوره 2016 شماره
صفحات -
تاریخ انتشار 2016